ACACA-Monoclonal Antibodies

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ACACA

Qty


Total
$300
Catalog #
A0110
Antibody Type
Monoclonal Antibody
Gene ID
31
Swiss Prot
Q13085
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IF IP
Recommended DilutionWB 1:200 - 1:2000 IF 1:50 - 1:200 IP 1:20 - 1:50
Calculated MW275kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human ACACA
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymACC; ACAC; ACC1; ACCA; ACACAD;
Images
  • A0110: image 1

    Western blot analysis of extracts of HeLa cell line, using ACACA antibody.

Background

Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene.

Protocol

N/A

MSDS
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