|Reactivity||Human Mouse Rat|
|Tested applications||WB IHC IF|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:20 - 1:100|
|Observed MW||Refer to Figures|
|Immunogen||Recombinant protein of human ALDOA|
|Storage Buffer||Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
Western blot analysis of extracts of various cell lines, using ALDOA antibody.
Immunofluorescence analysis of A549 cell using ALDOA antibody. Blue: DAPI for nuclear staining.
Aldolase (fructose bisphosphate aldolase), a glycolytic enzyme, catalyzes the conversion of fructose 1, 6-bisphosphate to 3-phosphoglyceraldehyde. This ubiquitous enzyme is present as three different isozymes: aldolase A, aldolase B, and aldolase C. Studies suggest the potential diagnostic value of quantitative analysis of aldolase A for hepatocarcinoma (1). Furthermore, the change in aldolase B gene expression levels has also been observed in certain patients with this primary tumor (2,3).
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