APOE-Monoclonal Antibodies

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APOE

Qty


Total
$220
Catalog #
A0304
Antibody Type
Polyclonal Antibody
Gene ID
348
Swiss Prot
P02649
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100
Calculated MW36kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human APOE
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymAPOE;AD2;LDLCQ5;LPG;MGC1571;
Images
  • A0304: image 1

    Western blot analysis of extracts of various cell lines, using APOE antibody.

  • A0304: image 2

    Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (40x lens).

  • A0304: image 3

    Immunohistochemistry of paraffin-embedded human stomach using ApoE antibody at dilution of 1:100 (40x lens).

  • A0304: image 4

    Immunohistochemistry of paraffin-embedded mouse lung using ApoE antibody at dilution of 1:100 (40x lens).

  • A0304: image 5

    Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (x40 lens).

  • A0304: image 6

    Immunohistochemistry of paraffin-embedded human prostate using ApoE antibody at dilution of 1:100 (x40 lens).

  • A0304: image 7

    Immunohistochemistry of paraffin-embedded human lung using ApoE antibody at dilution of 1:100 (x40 lens).

Background

The apolipoprotein E(APOE) is a 299-amino acid polypeptide that mediates the binding, internalization, and catabolism of lipoprotein particles, and also serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues. The very strong association of the APOE ɛ4 allele with AD risk and its role in the accumulation of amyloid β in brains of people and animal models solidify the biological relevance of apoE isoforms but do not provide mechanistic insight

Protocol

N/A

MSDS
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