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sales@neoscientific.com
+1-888.733.6849
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+1-888.733.6849
+1-617.299.7367 (Int’l)
| Reactivity | Human Mouse Rat Other (Wide Range) |
| Tested applications | WB IHC IF IP CHIP CHIPseq |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200 IP 1:50 - 1:200 ChIP 1:20 - 1:100 CHIPseq 1:20 - 1:100 |
| Calculated MW | 16kDa |
| Observed MW | Refer to figures |
| Immunogen | A synthetic methylated peptide corresponding to residues surrounding R2 of human histone H3 |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | qu |
| Synonym | H3R2me2a; H3t; H3.4; H3/g; H3FT; |
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.
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