CAV3-Monoclonal Antibodies

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CAV3

Qty


Total
$220
Catalog #
A8089
Antibody Type
Polyclonal Antibody
Gene ID
859
Swiss Prot
P56539
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200
Calculated MW17kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human CAV3
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymLQT9; VIP21; LGMD1C; VIP-21;
Images
  • A8089: image 1

    Western blot analysis of extract of various cells, using CAV3 antibody.

  • A8089: image 2

    Immunohistochemistry of paraffin-embedded human colon using CAV3 antibody at dilution of 1:200 (40x lens).

  • A8089: image 3

    Immunohistochemistry of paraffin-embedded mouse lung using CAV3 antibody at dilution of 1:200 (40x lens).

Background

This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Protocol

N/A

MSDS
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