COX4I1-Monoclonal Antibodies

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COX4I1

Qty


Total
$220
Catalog #
AC019
Antibody Type
Polyclonal Antibody
Gene ID
1327
Swiss Prot
P13073
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:10 - 1:100
Calculated MW19kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human COX4I1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymCOX4; COXIV; COX4-1;
Images
  • AC019: image 1

    Western blot analysis of extracts of various cell lines, using COX4I1 antibody.

  • AC019: image 2

    Immunofluorescence analysis of HeLa cell using COX4I1 antibody. Blue: DAPI for nuclear staining.

Background

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it.

Protocol

N/A

MSDS
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