EpCAM-Monoclonal Antibodies

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EpCAM

Qty


Total
$300
Catalog #
A0895
Antibody Type
Monoclonal Antibody
Gene ID
4072
Swiss Prot
P16422
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:2000
Calculated MW39kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human EpCAM
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymEPCAM;DIAR5;EGP-2;EGP314;EGP40;ESA;GA733-2;HNPCC8;KS1/4;KSA;M4S1;MIC18;MK-1;TACSTD1;TROP1;KSA;
Images
  • A0895: image 1

    Western blot analysis of extracts of HT-29 cells, using EpCAM antibody.

Background

Epithelial cell adhesion and activating molecule (EpCAM/CD326) is a transmembrane glycoprotein that mediates Ca2+-independent, homophilic adhesions on the basolateral surface of most epithelial cells. EpCAM is not expressed in adult squamous epithelium, but it is highly expressed in adeno and squamous cell carcinomas (1). One of the first tumor-associated antigens discovered, EpCAM has long been a marker of epithelial and tumor tissue. Because of its high expression in cancer, EpCAM has become a therapeutic target for human solid tumors of epithelial lineage (reviewed in 2,3).

Protocol

N/A

MSDS
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