HK2-Monoclonal Antibodies

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+1-617.299.7367 (Int’l)
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+1-617.299.7367 (Int’l)

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HK2

Qty


Total
$220
Catalog #
A0994
Antibody Type
Polyclonal Antibody
Gene ID
3099
Swiss Prot
P52789
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Calculated MW102kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human HK2
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymHK2;DKFZp686M1669;HKII;HXK2 ;
Images
  • A0994: image 1

    Western blot analysis of extracts of various cell lines, using HK2 antibody.

  • A0994: image 2

    Immunofluorescence analysis of U2OS cell using HK2 antibody. Blue: DAPI for nuclear staining.

Background

Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect) (1) in order to compensate for the increased energy demands associated with rapid cell growth and proliferation (2,3).

Protocol

N/A

MSDS
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