IFNB1-Monoclonal Antibodies

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IFNB1

Qty


Total
$220
Catalog #
A1575
Antibody Type
Polyclonal Antibody
Gene ID
3456
Swiss Prot
P01574
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Calculated MW22kDa
Observed MWRefer to Figures
ImmunogenRecombinant protein of human IFNB1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationb
SynonymIFNB1;IFB;IFF; IFNB;MGC96956;
Images
  • A1575: image 1

    Western blot analysis of extracts of various cell lines, using IFNB1 antibody.

  • A1575: image 2

    Immunohistochemistry of paraffin-embedded human kidney using IFNB1 antibody at dilution of 1:200 (x400 lens)

  • A1575: image 3

    Immunohistochemistry of paraffin-embedded human esophageal cancer using IFNB1 antibody at dilution of 1:200 (x400 lens)

  • A1575: image 4

    Immunofluorescence analysis of HepG2 cell using IFNB1 antibody. Blue: DAPI for nuclear staining.

Background

The genes encoding type I interferons (IFNs), which include 14 IFN-å genes, one IFN-∫ gene, one IFN-w (also known as IFN-å II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-å and -∫ are cytokines that are widely known to induce potent antiviral activity. IFN-å and -∫ exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-å, IFN-∫ or IFN-©, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-åR) interacts with IFN-å, IFN-∫ and IFN-w, and seems to be a multisubunit receptor.

Protocol

N/A

MSDS
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