ORAI1-Polyclonal Antibodies

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ORAI1

Qty


Total
$220
Catalog #
A7412
Antibody Type
Polyclonal Antibody
Gene ID
84876
Swiss Prot
Q96D31
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat Zebrafish
Tested applicationsWB IF
Recommended DilutionWB 1:200 - 1:2000 IF 1:10 - 1:100
Calculated MW33kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human ORAI1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymIMD9; TAM2; ORAT1; CRACM1; TMEM142A;
Images
  • A7412: image 1

    Western blot analysis of extracts of Jurkat cell line, using ORAI1 antibody.

Background

The protein encoded by this gene is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).

Protocol

N/A

MSDS
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