PRKD3-Monoclonal Antibodies

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PRKD3

Qty


Total
$220
Catalog #
A7084
Antibody Type
Polyclonal Antibody
Gene ID
23683
Swiss Prot
O94806
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:100
Calculated MW100kDa
Observed MWRefer to figures
ImmunogenRecombinant protein of human PRKD3
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SynonymEPK2; PKD3; PRKCN; PKC-NU; nPKC-NU;
Images
  • A7084: image 1

    Western blot analysis of extracts of various cell lines, using PRKD3 antibody.

  • A7084: image 2

    Immunofluorescence analysis of A549 cell using PRKD3 antibody. Blue: DAPI for nuclear staining.

Background

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members.

Protocol

N/A

MSDS
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