Phospho-AMPKα-T172-Monoclonal Antibodies

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Phospho-AMPKα-T172

Qty


Total
$300
Catalog #
AP0116
Antibody Type
Polyclonal Antibody
Gene ID
5562
Swiss Prot
Q13131
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman
Tested applicationsWB
Recommended DilutionWB 1:500 - 1:1000
Calculated MW64kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding T172 of human AMPKα
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationbch
SynonymAMPK; AMPKa1;
Images
  • AP0116: image 1

    Western blot analysis of extracts of various cell lines, using Phospho-AMPKα-T172 antibody.

Background

The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Protocol

N/A

MSDS
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