Phospho-EZR-Y353-Polyclonal Antibodies

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Phospho-EZR-Y353

Qty


Total
$300
Catalog #
AP0349
Antibody Type
Polyclonal Antibody
Gene ID
7430
Swiss Prot
P15311
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100
Calculated MW81kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding Y353 of human EZR
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationj
SynonymCVL; CVIL; VIL2;
Images
  • AP0349: image 1

    Western blot analysis of extracts from 293 cells, using Phospho-EZR-Y353 antibody.

  • AP0349: image 2

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-EZR-Y353 antibody.

Background

The cytoplasmic peripheral membrane protein encoded by this gene functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for this gene. Alternatively spliced variants have also been described for this gene.

Protocol

N/A

MSDS
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