Phospho-RPS6KB1-T421-Polyclonal Antibodies

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Phospho-RPS6KB1-T421

Qty


Total
$300
Catalog #
AP0449
Antibody Type
Polyclonal Antibody
Gene ID
6198
Swiss Prot
P23443
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200
Calculated MW56-59kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding T421 of human RPS6KB1
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationr
SynonymS6K; PS6K; S6K1; STK14A; p70-S6K; p70 S6KA; p70-alpha; S6K-beta-1; p70(S6K)-alpha;
Images
  • AP0449: image 1

    Western blot analysis of extracts from Jurkat cells, using Phospho-RPS6KB1-T421 Antibody.

  • AP0449: image 2

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue, using Phospho-RPS6KB1-T421 Antibody.

  • AP0449: image 3

    Immunofluorescence staining of methanol-fixed MCF cells, using Phospho-RPS6KB1-T421 Antibody.

Background

This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17.

Protocol

N/A

MSDS
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