Phospho-SRC-Y529-Polyclonal Antibodies

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Phospho-SRC-Y529

Qty


Total
$300
Catalog #
AP0185
Antibody Type
Polyclonal Antibody
Gene ID
6714
Swiss Prot
P12931
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:100 IF 1:100 - 1:200
Calculated MW60kDa
Observed MWRefer to Figures
ImmunogenA phospho specific peptide corresponding to residues surrounding Y529 of human SRC
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationoqt
SynonymASV; SRC1; c-SRC; p60-Src;
Images
  • AP0185: image 1

    Western blot analysis of extracts from HT29 cells, using Phospho-SRC-Y529 antibody.

  • AP0185: image 2

    Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Phospho-SRC-Y529 antibody.

  • AP0185: image 3

    Immunofluorescence staining of methanol-fixed Hela cells using Phospho-SRC-Y529 antibody.

Background

This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.

Protocol

N/A

MSDS
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