RPS6-Monoclonal Antibodies

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RPS6

Qty


Total
$220
Catalog #
A0932
Antibody Type
Monoclonal Antibody
Gene ID
6194
Swiss Prot
P62753
Size
Species
Mouse
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC IF FC
Recommended DilutionWB 1:500 - 1:1000 IHC 1:50 - 1:200 IF 1:20 - 1:50 FC 1:20 - 1:50
Calculated MW29kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human RPS6
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationjq
SynonymRPS6; 40S ribosomal protein S6; Phosphoprotein NP33;
Images
  • A0932: image 1

    Western blot analysis of extracts of 293 cell lines, using RPS6 antibody.

Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Protocol

N/A

MSDS
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