|Reactivity||Human Mouse Rat|
|Tested applications||WB IHC IF IP CHIP|
|Recommended Dilution||WB 1:500 - 1:2000
IHC 1:50 - 1:200
IF 1:50 - 1:200
IP 1:50 - 1:200
ChIP 1:20 - 1:100|
|Observed MW||Refer to Figures|
|Immunogen||Recombinant protein of human SMARCC1|
|Storage Buffer||Store at -20℃. Avoid freeze / thaw cycles.
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.|
|Synonym||Rsc8; SRG3; SWI3; BAF155; CRACC1;|
Western blot analysis of extracts of various cell lines, using SMARCC1 antibody.
Immunohistochemistry of paraffin-embedded human kidney cancer using SMARCC1 antibody at dilution of 1:200 (400x lens).
The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors.
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