SNCA-Polyclonal Antibodies

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SNCA

Qty


Total
$220
Catalog #
A0012
Antibody Type
Polyclonal Antibody
Gene ID
6622
Swiss Prot
P37840
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse Rat
Tested applicationsWB IHC FC
Recommended DilutionWB 1:200 - 1:2000 IHC 1:50 - 1:200 FC 1:20 - 1:50
Calculated MW14kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human SNCA
Storage BufferStore at 4℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationbi
SynonymTLR7-like;
Images
  • A0012: image 1

    Western blot analysis of extracts of various cell lines, using SNCA antibody.

Background

SNCA, also named as NACP, PARK1 and Alpha-synuclein, belongs to the synuclein family. It may be involved in the regulation of dopamine release and transport. SNCA reduces neuronal responsiveness to various apoptotic stimuli, leading to a decreased caspase-3 activation. The deposition of aggregated SNCa is the pathological hallmark of Lewy body disease, which includes Parkinson’s disease (PD), diffuse Lewy body disease (DLBD), and Lewy body variant of Alzheimer’s disease (LBV).(PMID:21056999) This antibody can recognize all the isoforms of SNCA.

Protocol

N/A

MSDS
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