STAT6-Monoclonal Antibodies

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STAT6

Qty


Total
$380
Catalog #
A0755
Antibody Type
Polyclonal Antibody
Gene ID
6778
Swiss Prot
P42226
Size
Species
Rabbit
Isotype
IgG
Purity
Affinity purification
Additional Information
ReactivityHuman Mouse
Tested applicationsWB IHC ICC IP
Recommended DilutionWB 1:500 - 1:2000 IHC 1:50 - 1:200 ICC 1:50 - 1:100 IP 1:50 - 1:100
Calculated MW100kDa
Observed MWRefer to Figures
ImmunogenA synthetic peptide of human STAT6
Storage BufferStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentrationko
SynonymSTAT6B; STAT6C; D12S1644; IL-4-STAT;
Images
  • A0755: image 1

    Western blot analysis of extracts of NIH3T3 cell line, using STAT6 antibody.

Background

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein plays a central role in exerting IL4 mediated biological responses. It is found to induce the expression of BCL2L1/BCL-X(L), which is responsible for the anti-apoptotic activity of IL4. Knockout studies in mice suggested the roles of this gene in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins. Alternative splicing results in multiple transcript variants.

Protocol

N/A

MSDS
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