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+1-888.733.6849
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| Reactivity | Human Mouse Rat |
| Tested applications | WB IHC |
| Recommended Dilution | WB 1:500 - 1:2000 IHC 1:50 - 1:100 |
| Calculated MW | 17kDa |
| Observed MW | Refer to figures |
| Immunogen | Recombinant protein of human UBE2A |
| Storage Buffer | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| Concentration | efl |
| Synonym | UBC2; HHR6A; MRXSN; RAD6A; MRXS30; |
Western blot analysis of extracts of mouse kidney, using UBE2A antibody.
Immunohistochemistry of paraffin-embedded mouse stomach using UBE2A antibody.
Immunohistochemistry of paraffin-embedded rat brain using UBE2A antibody.
Immunohistochemistry of paraffin-embedded human esophagus using UBE2A antibody.
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair, and may play a role in transcriptional regulation. Mutations in this gene are associated with mental retardation. Alternative splicing results in multiple transcript variants.
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