AKR7A3 Human-Reductase

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AKR7A3 Human

Qty


Total
$65
Catalog #
ENPS-491
Size
Description
AKR7A3 Human Recombinant fused to 39 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 370 amino acids (1-331 a.a.)and having a molecular mass of 41.6 kDa. The AKR7A3 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionAKR7A3, takes part in the detoxification of aldehydes and ketones.AKR7A3 reduces the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. AKR7A3 participates in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen.
SynonymsAFAR2, Aflatoxin B1 aldehyde reductase member 3, AFB1 aldehyde reductase 2, AFB1-AR 2, AKR7A3.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear colorless solution.
FormulationThe AKR7A3 solution contains 20mM Tris-HCl pH-8, 0.1M NaCl and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMRGSHHHHHH
GMASMTGGQQ
MGRDLYDDDD
KDRWGSELEM
SRQLSRARPA
TVLGAMEMGR
RMDAPTSAAV
TRAFLERGHTEIDTAFVYSE
GQSETILGGL
GLRLGGSDCR
VKIDTKAIPL
FGNSLKPDSL
RFQLETSLKR
LQCPRVDLFY
LHMPDHSTPV
EETLRACHQL
HQEGKFVELG
LSNYAAWEVA
EICTLCKSNG
WILPTVYQGM
YNAITRQVET
ELFPCLRHFG
LRF
PurityGreater than 95.0% as determined by SDS-PAGE.
Biological ActivitySpecific activity: approximately < 0.1 units/mg.Enzymatic activity was confirmed by measuring the amount of enzyme catalyzing the oxidation of 1 micromole NADPH per minute at 25C. Specific activity was expressed as units/mg protein.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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