ANXA5 Human-Annexin

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ANXA5 Human

Qty


Total
$65
Catalog #
PRPS-739
Size
Description
ANXA5 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 320 amino acids (1-320 a.a.) and having a molecular mass of 35.9 kDa.ANXA5 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionANXA5 is a member of the annexin family of calcium-dependent phospholipid binding proteins which are involved in membrane-related activity along exocytotic and endocytotic pathways. ANXA5 is a phospholipase A2 and protein kinase C inhibitory protein with calcium channel properties and takes part in cellular signal transduction, inflammation, growth and differentiation. ANXA5 is an anticoagulant protein that acts as an indirect inhibitor of the thromboplastin-specific complex, which is involved in the blood coagulation cascade. ANXA5 regulates coagulability in the blood stream by binding to phosphatidylserine and sulfatide. ANXA5 protects sinsuoidal endothelial cells from ischemia reperfusion damage. ANXA5 is necessary for normal CFTR chloride channel activity.
SynonymsPP4, ANX5, ENX2, ANXA5, Annexin A5, Annexin-5, Annexin V, Lipocortin V, Endonexin II, Calphobindin I, CBP-I, Placental anticoagulant protein I, PAP-I, Placental anticoagulant protein 4, Thromboplastin inhibitor, Vascular anticoagulant-alpha, VAC-alpha, An
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationThe ANXA5 protein solution contains 20mM Tris-HCl, pH-8, 1mM DTT and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMAQVLRGTVT
DFPGFDERAD
AETLRKAMKG
LGTDEESILT
LLTSRSNAQR
QEISAAFKTL
FGRDLLDDLK
SELTGKFEKL
IVALMKPSRL
YDAYELKHAL
KGAGTNEKVL
TEIIASRTPE
ELRAIKQVYE
EEYGSSLEDD
VVGDTSGYYQ
RMLVVLLQAN
RDPDAGIDEA
QVEQDAQALF
QAGELKWGTD
EEKFITIFGT
RSVSHLRKVF
DKYMTISGFQ
IEETIDRETS
GN
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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