Apoliprotein-D is mainly associated with high density lipoproteins in human plasma. Apoliprotein-D is an atypical Apoliprotein and, based on its primary structure, Apoliprotein-D is a member of the lipocalin family. Lipocalins adopt a beta-barrel tertiary structure and transport small hydrophobic ligands. Apoliprotein-D binds cholesterol, progesterone, pregnenolone, bilirubin and arachidonic acid. Apoliprotein-D is expressed in numerous tissues having high levels of expression in spleen, testes and brain. Apoliprotein-D is present at high concentrations in the cyst fluid of women with gross cystic disease of the breast, a condition associated with increased risk of breast cancer. Apoliprotein-D accumulates in regenerating peripheral nerves and in the cerebrospinal fluid of patients with neurodegenerative conditions, such as Alzheimer's disease. Apoliprotein-D participates in maintenance and repair within the central and peripheral nervous systems. Apoliprotein-D is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another within an organ, scavenge a ligand within an organ for transport to the blood or could transport a ligand from the circulation to specific cells within a tissue.
Apoliprotein D, Apo-D, ApoD.
Sterile Filtered clear solution.
APO-D protein at 100
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.
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