C1QTNF3 Human-Complement Component

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C1QTNF3 Human

Qty


Total
$65
Catalog #
PRPS-660
Size
Description
C1QTNF3 Human Recombinant produced in E.Coli is a single, non-glycosylated, Polypeptide chain containing 234 amino acids and having a molecular mass of 25.4 kDa. The protein contains an extra 10 aa His tag at N-terminus. The C1QTNF3 amino acid sequence is identical to UniProtKB/Swiss-Prot entry Q9BXJ4 amino acids 23–246. The C1QTNF3 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionC1QTNF3 also called Cartducin is a novel angiogenic factor in the formation of neointima following angioplasty. C1QTNF3 a paralog of Acrp30 (adiponectin). C1QTNF3 is a secretory protein produced by chondrogenic precursors & proliferating chondrocytes, and belongs to a novel C1q family of proteins. Cartducin promotes the growth of mesenchymal chondroprogenitor cells & chondrosarcoma-derived chondrocytic cells in vitro. Cartducin stimulates mesenchymal chondroprogenitor cell proliferation throµgh extracellular signal-regulated kinase and phosphatidylinositol 3-kinase/Akt pathways. C1QTNF3 promotes proliferation & the migration of endothelial cells.
SynonymsComplement C1q tumor necrosis factor-related protein 3, Secretory protein CORS26, C1QTNF3, CTRP3, Cors, Corcs, CORS26, FLJ37576, Cartducin.
SourceEscherichia Coli.
FormulationHuman C1QTNF3 was filtered (0.4
SolubilityIt is recommended to add 0.1M Acetate buffer pH4 to prepare a working stock solution of approximately 0.5 mg/ml and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10
StabilityStore lyophilized C1QTNF3 at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted C1QTNF3 can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C.
Amino Acid SequenceMKHHHHHHAS
QDEYMESPQT
GGLPPDCSKC
CHGDYSFRGY
QGPPGPPGPP
GIPGNHGNNG
NNGATGHEGA
KGEKGDKGDL
GPRGERGQHG
PKGEKGYPGI
PPELQIAFMA
SLATHFSNQN
SGIIFSSVET
NIGNFFDVMT
GRFGAPVSGV
YFFTFSMMKH
EDVEEVYVYL
MHNGNTVFSM
YSYEMKGKSD
TSSNHAVLKL
AKGDEVWLRM
GNGALHGDHQ
RFSTFAGFLLFET
PurityThe purity of C1QTNF3 is greater than 95% as determined by SDS PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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