C9ORF95 Human-Chromosome Open Reading Frame

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C9ORF95 Human

Qty


Total
$65
Catalog #
PRPS-1123
Size
Description
C9ORF95 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 222 amino acids (1-199 a.a) and having a molecular mass of 25.6kDa.C9ORF95 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionChromosome 9 Open Reading Frame 95 (C9ORF95/NRK1) is a member of the uridine kinase family. NAD+ is vital for life in all organisms, both as a coenzyme for oxidoreductases and as a source of ADPribosyl groups used in countless reactions, including those which delay aging in experimental systems. Nicotinic acid and nicotinamide are defined as the vitamin precursors of NAD+. C9ORF95 catalyzes the phosphorylation of nicotinamide riboside (NR) and nicotinic acid riboside (NaR) to form nicotinamide mononucleotide (NMN) and nicotinic acid mononucleotide (NaMN). C9ORF95 also phosphorylates the antitumor drµgs tiazofurin and 3-deazaguanosine.
SynonymsNicotinamide riboside kinase 1, NRK 1, NmR-K 1, Nicotinic acid riboside kinase 1, Ribosylnicotinamide kinase 1, RNK 1, Ribosylnicotinic acid kinase 1, NMRK1, C9orf95, NRK1, bA235O14.2, RP11-235O14.2.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationC9ORF95 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer, pH8.0, 10% glycerol, 2mM DTT and 200mM NaCl.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMKTFIIG
ISGVTNSGKT
TLAKNLQKHL
PNCSVISQDD
FFKPESEIET
DKNGFLQYDV
LEALNMEKMM
SAISCWMESA
RHSVVSTDQE
SAEEIPILII
EGFLLFNYKP
LDTIWNRSYF
LTIPYEECKR
RRSTRVYQPP
DSPGYFDGHV
WPMYLKYRQE
MQDITWEVVY
LDGTKSEEDL
FLQVYEDLIQ
ELAKQKCLQV
TA.
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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