CA3 Human-Carbonic Anhydrase

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CA3 Human

Qty


Total
$65
Catalog #
ENPS-507
Size
Description
CA3 Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 260 amino acids (1-260 a.a.)and having a molecular mass of 29.5 kDa. The CA3 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionCarbonic anhydrase III is part of a multigene family that encodes carbonic anhydrase isozymes which are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in various cell types. Carbonic anhydrase III expression is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. CA3 catalyses swift conversion of carbon dioxide to bicarbonate and protons (CO2 + H2O = HCO3 + H+). CA3 participates in a variety of biological processes, including respiration, calcifica-tion, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. CA3 includes a zinc ion in its active site and maintains acid-base balance in blood and other tissues, and to help transport carbon dioxide of tissues.
SynonymsCar3, CAIII, Carbonic anhydrase 3, EC 4.2.1.1, Carbonic anhydrase III, Carbonate dehydratase III, CA-III.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear colorless solution.
FormulationThe CA3 solution contains 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
StabilityCA3 Recombinant Human althoµgh stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
Amino Acid SequenceMAKEWGYASH
NGPDHWHELF
PNAKGENQSP
IELHTKDIRH
DPSLQPWSVS
YDGGSAKTIL
NNGKTCRVVF
DDTYDRSMLR
GGPLPGPYRL
RQFHLHWGSS
DDHGSEHTVD
GVKYAAELHL
VHWNPKYNTF
KEALKQRDGI
AVIGIFLKIG
HENGEFQIFL
DALDKIKTKG
KEAPFTKFDP
SCLFPACRDY
WTYQGSFTTP
PCEECIVWLL
LKEPMTVSSD
QMAKLRSLLS
SA
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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