CCNB1 Human-Cyclin

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CCNB1 Human

Qty


Total
$65
Catalog #
PKPS-044
Size
Description
CCNB1 Human Recombinant produced in E. coli is a single polypeptide chain containing 457 amino acids (1-433) and having a molecular mass of 50.9 kDa.CCNB1 is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionCyclin B1 (CCNB1) is a regulatory protein involved in mitosis. CCNB1 creates a complex with p34(cdc2) to form the maturation-promoting factor (MPF). CCNB1 is vital for the control of the cell cycle at the G2/M (mitosis) transition. CCNB1 builds up steadily during the G2 and is immediately destroyed at mitosis. The 2 alternative transcripts produce a constitutively expressed transcript and a cell cycle-regulated transcript which is expressed predominantly during G2/M phase. These transcripts are a result of alternate transcription initiation sites.
SynonymsG2/mitotic-specific cyclin-B1, cyclin B1, CCNB.
SourceE.coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CCNB1 solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 150mM NaCl and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSHMALRVT
RNSKINAENK
AKINMAGAKR
VPTAPAATSK
PGLRPRTALG
DIGNKVSEQL
QAKMPMKKEA
KPSATGKVID
KKLPKPLEKV
PMLVPVPVSE
PVPEPEPEPE
PEPVKEEKLS
PEPILVDTAS
PSPMETSGCA
PAEEDLCQAF
SDVILAVNDV
DAEDGADPNL
CSEYVKDIYA
YLRQLEEEQA
VRPKYLLGRE
VTGNMRAILI
DW
PurityGreater than 80% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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