CDCA8 Human-Cell Division Cycle

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CDCA8 Human

Qty


Total
$65
Catalog #
PRPS-229
Size
Description
CDCA8 Human Recombinant fused with a 21 amino acid His tag at N-terminus produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 283 amino acids (19-280a.a.) and having a molecular mass of 31.6kDa. The CDCA8 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionCDCA8 is a component of the chromosomal passenger complex (CPC). The CPC complex has crucial functions at the centromere in ensuring accurate chromosome placement and isolation and is obligatory for chromatin-induced microtubule stabilization and spindle assembly. In the complex, CDCA8 protein is needed to direct the CPC to centromeric DNA. Removal of CDCA8 delays mitotic progression and causes kinetochore-spindle to mis-attach.
SynonymsCell division cycle associated 8, BOR, hDasraB, FLJ12042, MESRGP, Pluripotent embryonic stem cell-related gene 3 protein, PESCRG3, BOREALIN.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CDCA8 solution (0.25mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 50% glycerol, 1mM DTT, 1mM EDTA and 0.2M NaCl.
StabilityCDCA8 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MRKLASFLKD
FDREVEIRIK
QIESDRQNLL
KEVDNLYNIE
ILRLPKALRE
MNWLDYFALG
GNKQALEEAA
TADLDITEIN
KLTAEAIQTP
LKSAKTRKVI
QVDEMIVEEE
EEEENERKNL
QTARVKRCPP
SKKRTQSIQG
KGKGKRSSRA
NTVTPAVGRLEVSMVKPTPG
LTPRFDSRVF
KTPGLRTPAA
GERIYNISGN
GSPLADSKEI
FLT
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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