CLIC2 Human-Chloride Intracellular Channel

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CLIC2 Human

Qty


Total
$65
Catalog #
PRPS-205
Size
Description
CLIC2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 267 amino acids (1-247 a.a.) and having a molecular mass of 30.5kDa.CLIC2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionChloride intracellular channel protein 2 (CLIC2) regulates cellular traffic of chloride ions, which is a critical component of all living cells. CLIC2 is involved in membrane potential stabilization, signal transduction, cell volume regulation and organic solute transport. CLIC2 is identified in the fetal liver and adult skeletal muscle tissue. CLIC2 is a likely candidate for one of the many diseases linked to Xq28.
SynonymsChloride intracellular channel protein 2, XAP121, CLIC2, CLIC2b, XAP121.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe CLIC2 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 20% glycerol 0.1M NaCl and 1mM DTT.
StabilityCLIC2 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSGLRPGTQV
DPEIELFVKA
GSDGESIGNC
PFCQRLFMIL
WLKGVKFNVT
TVDMTRKPEE
LKDLAPGTNP
PFLVYNKELK
TDFIKIEEFL
EQTLAPPRYP
HLSPKYKESF
DVGCNLFAKF
SAYIKNTQKE
ANKNFEKSLL
KEFKRLDDYL
NTPLLDEIDPDSAEEPPVSR
RLFLDGDQLT
LADCSLLPKL
NIIKVAAKKY
RDFDIPAEFS
GVW
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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