DCXR Human-Reductase

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DCXR Human

Qty


Total
$65
Catalog #
ENPS-547
Size
Description
DCXR Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 264 amino acids (1-244 a.a.) and having a molecular mass of 28 kDa. The DCXR is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionDCXR catalyzes the NADPH-dependent reduction of numerous pentoses, tetroses, trioses, alpha-dicarbonyl molecules and L-xylulose. DCXR takes part in the uronate cycle of glucose metabolism. DCXR participates in the water absorption andcellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thus preventing osmolytic stress from occurring in the renal tubules.
SynonymsDCR, HCR2, HCRII, KIDCR, P34H, SDR20C1, Dicarbonyl/L-Xylulose Reductase, EC=1.1.1.10, Carbonyl reductase II, Kidney dicarbonyl reductase, Sperm surface protein P34H.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationDCXR Human solution containing 20mM Tris-HCl pH-8, 1mM DTT, 50mM NaCl & 20% glycerol.
StabilityDCXR Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MELFLAGRRV
LVTGAGKGIG
RGTVQALHAT
GARVVAVSRT
QADLDSLVRE
CPGIEPVCVD
LGDWEATERA
LGSVGPVDLL
VNNAAVALLQ
PFLEVTKEAF
DRSFEVNLRA
VIQVSQIVAR
GLIARGVPGA
IVNVSSQCSQ
RAVTNHSVYC
STKGALDMLT
KVMALELGPH
KIRVNAVNPT
VVMTSMGQAT
WSDPHKAKTM
LNRIPLGKFA
EV
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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