The E.coli derived recombinant 15kDa protein is genetically engineered peptide which is derived from Dengue Type-4 envelope III domain immunodeterminant regions. The expressed dengue envelope Type-4 III domain peptide has 100 amino acids covering domain III region from amino acids 300-400, and is fused with a 6 His Tag. This peptide is particularly important for diagnostic and vaccine development as it contains multiple serotypes, neutralizing epitopes and receptor binding domain.
Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. In cell culture experiments and mice Morpholino antisense oligos have shown specific activity against Dengue virus.
1xPBS pH 7.4.
Protein is >95% pure as determined by 12% PAGE (coomassie staining).
NeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Each laboratory should determine an optimum working titer for use in its particular application.
Dengue Envelope-ST4 D-III althoµgh stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.