DIMT1 Human-Transferase

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DIMT1 Human

Qty


Total
$65
Catalog #
ENPS-635
Size
Description
DIMT1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 334 amino acids (1-313) and having a molecular mass of 37.5kDa.DIMT1 is fused to a 21 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionDIM1 dimethyladenosine transferase 1 homolog (DIMT1) is a member of the methyltransferase superfamily. The DIMT1 enzyme specifically dimethylates 2 adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 18S rRNA in the 40S particle. DIMT1 is restricted to the nucleolus.
SynonymsProbable dimethyladenosine transferase, DIM1 dimethyladenosine transferase 1 homolog, DIM1 dimethyladenosine transferase 1-like, Probable 18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase, Probable 18S rRNA dimethylase, Probable S-adeno
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe DIMT1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer, pH8.0, 30% glycerol, 2mM DTT, 200mM NaCl and 2mM EDTA.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MMPKVKSGAI
GRRRGRQEQR
RELKSAGGLM
FNTGIGQHIL
KNPLIINSII
DKAALRPTDV
VLEVGPGTGN
MTVKLLEKAK
KVVACELDPR
LVAELHKRVQ
GTPVASKLQV
LVGDVLKTDL
PFFDTCVANL
PYQISSPFVF
KLLLHRPFFR
CAILMFQREF
ALRLVAKPGD
KLYCRLSINT
QLLARVDHLM
KVGKNNFRPP
PKVESSVVRI
EP
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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