DRG1 Human-Other

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DRG1 Human

Qty


Total
$65
Catalog #
PRPS-892
Size
Description
DRG1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 387 amino acids (1-367 a.a.) and having a molecular mass of 42.7kDa.DRG1 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionDevelopmentally-regulated GTP-binding protein 1 (DRG1) is a member of the GTP1/OBG family. DRG1 has a role in cell proliferation and differentiation, as well as in apoptosis, proposing a role in tumor formation and metastasis. Expression of the DRG1 was considerably reduced in breast tumor cells, particularly in patients with lymph node or bone metastasis as compared to those with localized breast cancer. The DRG1 protein is expressed at high levels in the heart, kidney and skeletal muscle and at lower levels in the brain, liver, placenta, lung, colon and spleen.
SynonymsDevelopmentally-regulated GTP-binding protein 1, DRG-1, Neural precursor cell expressed developmentally down-regulated protein 3, NEDD-3, DRG1, NEDD3.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationDRG1 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1mM DTT, 30% glycerol and 1mM EDTA.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSSTLAKIAE
IEAEMARTQK
NKATAHHLGL
LKARLAKLRR
ELITPKGGGG
GGPGEGFDVA
KTGDARIGFV
GFPSVGKSTL
LSNLAGVYSE
VAAYEFTTLT
TVPGVIRYKG
AKIQLLDLPG
IIEGAKDGKG
RGRQVIAVAR
TCNLILIVLD
VLKPLGHKKI
IENELEGFGI
RLNSKPPNIG
FKKKDKGGIN
LTATCPQSEL
DAETVKSILA
EY
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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