EDN3 Human-Endothelin

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EDN3 Human

Qty


Total
$169
Catalog #
HOPS-316
Size
Description
EDN3 contains 21 amino acids having a molecular mass of 2634.1 Dalton.
Additional Information
IntroductionEDN3 interacts with endothelin receptor B, on the surface of cells. Throµghout embryonic development, EDN3 takes part in neural crest cells that migrate from the developing spinal cord to specific regions in the embryo, where they give rise to many different types of cells. EDN3 and EDN3R are necessary for the formation of nerves in the large intestine (enteric nerves) and melanocytes (produce melanin). Mutations in the EDN3 gene is linked with Waardenburg syndrome, type IV that is characterized by changes in skin, hair, and eye coloring. Mutations in the EDN3 gene is linked with Hirschsprung disease that causes severe constipation or intestinal blockage.
SynonymsEDN3, EDN-3, ET-3, ET3, WS4B, HSCR4, MGC15067, MGC61498, Endothelin-3, Preproendothelin-3, PPET3.
SourceNULL
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationThe protein (1mg/ml) was lyophilized with no additives.
SolubilityIt is recommended to reconstitute the lyophilized EDN3 in sterile 18MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
StabilityLyophilized EDN3 althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution EDN3 should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Amino Acid SequenceCys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp.
PurityGreater than 95.0% as determined by RP-HPLC.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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