Neuron Specific Neuron Specific Enolase Human Recombinant is expressed in E. coli containing 433 amino acids 2-434 fused to an amino terminal hexahistidine tag.The NSE is purified by proprietary chromatographic techniques.
NSE is the ?? isoform of the glycolytic enzyme Neuron Specific Enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival.
Gamma-Neuron Specific Enolase, EC 126.96.36.199, 2-phospho-D-glycerate hydro-lyase, Neural Neuron Specific Enolase, Neuron-specific Neuron Specific Enolase, NSE, Neuron Specific Enolase 2, ENO2.
Sterile Filtered clear solution.
Neuron Specific Enolase 2 is supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol.
Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Please prevent freeze-thaw cycles.
Greater than 95% as determined by SDS-PAGE. Single band on Western Blot.
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