FBP1 Human-Phosphatase

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FBP1 Human

Qty


Total
$65
Catalog #
ENPS-461
Size
Description
The FBP1 Human recombinant protein is a single, non-glycosilated polypeptide chain produced in E. coli, having a molecular weight of 39kDa and containing 358 amino acids (1-338 a.a.). The FBP1 enzyme is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatography techniques.
Additional Information
IntroductionFBP1 is a gluconeogenesis regulatory protein which catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate. FBP1 deficiency is associated with hypoglycemia and metabolic acidosis. FBP1 regulates mouse endogenous glucose production. FBP1 coupled with phosphofructokinase (PFK) takes part in the metabolism of pancreatic islet cells.
SynonymsFBP1, FBP, D-fructose-1,6-bisphosphate 1-phosphohydrolase 1, FBPase 1, Fructose-1,6-bisphosphatase 1.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe FBP1 protein solution is formulated in 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MADQAPFDTD
VNTLTRFVME
EGRKARGTGE
LTQLLNSLCT
AVKAISSAVR
KAGIAHLYGI
AGSTNVTGDQ
VKKLDVLSND
LVMNMLKSSF
ATCVLVSEED
KHAIIVEPEK
RGKYVVCFDP
LDGSSNIDCL
VSVGTIFGIY
RKKSTDEPSE
KDALQPGRNL
VAAGYALYGS
ATMLVLAMDC
GVNCFMLDPA
IGEFILVDKD
VKIKKKGKIY
SL
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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