FTH1 Human-Ferritin

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FTH1 Human

Qty


Total
$65
Catalog #
PRPS-665
Size
Description
FTH1 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 183 amino acids and having a molecular mass of 21 kDa.
Additional Information
IntroductionFerritin is a fairly large, iron-storage heteropolymeric protein composed of 2 subunit types, light Ferritin & heavy Ferritin polypeptides, which is expressed in most kinds of cells and co-assemble in different proportion in a tissue-specific manner. Ferritin is composed of 24 self-assembled polypeptide subunits of the heavy and light ferritin chains and is characterized by the capacity to remove Fe (II) from solution in the presence of oxygen. Ferritin light polypeptide protein is the main intracellular iron storage protein in prokaryotes and eukaryotes. Variation in ferritin subunit composition influence the rates of iron uptake and release in various tissues. A key function of ferritin is the storage of iron in a soluble and nontoxic state. Defects in this light chain ferritin gene are associated with several neurodegenerative diseases and hyper ferrit anemia-cataract syndrome. Ferritin stores iron in a soluble, nontoxic, readily accessible form. Ferritin is needed for iron homeostasis. Iron is taken up in the ferrous form and deposited as ferric hydroxides after it has been oxidized.
SynonymsFerritin heavy chain, Cell proliferation-inducing gene 15 protein, FTH1, FHC, FTH, PLIF, FTHL6, PIG15, MGC104426.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationThe FTH1 protein solution contains 20mM Tris-HCl pH-7.5, 1mM DTT and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMTTASTSQVR
QNYHQDSEAA
INRQINLELY
ASYVYLSMSY
YFDRDDVALK
NFAKYFLHQS
HEEREHAEKL
MKLQNQRGGR
IFLQDIKKPD
CDDWESGLNA
MECALHLEKN
VNQSLLELHK
LATDKNDPHL
CDFIETHYLN
EQVKAIKELG
DHVTNLRKMG
APESGLAEYL
FDKHTLGDSD
NES.
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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