HPV 18-Papillomavirus

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HPV 18

Qty


Total
$195
Catalog #
HPPS-009
Size
Description
The Recombinant HPV-18 (a 56kDa antigen) comprised from the E2, E6 & E7 epitopes is expressed in E. coli and fused to a GST-Tag, having a total Mw of 83kDa, purified by standard chromatography.
Additional Information
IntroductionHuman papillomavirus family consist of over 200 types. Over than 30 to 40 types of HPV are transferred via sexual contact and infect the anogenital region initiating genital warts. Persistent infection with "high-risk" HPV types results in skin warts and leads to precancerous lesions and invasive cancer. HPV infection is considered as a source for all incidents of cervical cancer. E2, E6, and E7 proteins of HPV-16 and 18 are considered the main viral oncoproteins that take part in cervical cancer. The type-specific antigen epitopes of E2, E6, and E7 proteins of HPV-16 are fused together and expressed in E. coli for diagnostic purpose.
SynonymsPapillomavirus, HPV, Papilloma Virus.
SourceE.Coli
Physical AppearanceSterile filtered clear liquid formulation.
FormulationThe protein is formulated with 1xPBS, 20mM arginine and 0.02% sodium azide as preservative.
Amino Acid SequenceVDVYLPPPSVARVVNTDDYVTPTSIFYHAGSSRLLTVGNPYFRVPAGGGNKQDIPKVSAYQYRVFRVQLPDPNKFGLPDTSIYNPETQRLVWACAGVEIGRGQPLGVGLSGHPFYNKLDDTESSHAATSNVSEDVRDNVSVDYKQTQLCILGCAPAIGEHWAKGTACKSRPLSQGDCPPLELKNTVLEDGDMVDTGYGAMDFSTLQDTKCEVPLDICQSICKYPDYLQMSADPYGDSMFFCLRREQLFARHFWNR
PurityProtein is >95% pure as determined by 12% PAGE (Coomassie staining).
UsageNeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
ApplicationsImmunoassay.
Purification MethodThe recombinant HPV-16 fusion protein was purified by GSH affinity chromatography technique.
Background

N/A

Protocol

N/A

MSDS
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