HTLV-I+II-HTLV

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HTLV-I+II

Qty


Total
$65
Catalog #
HIPS-122
Size
Description
E.coli derived recombinant 56kDa protein, (Purified/Coating; EIA), strain: BL21 DE3(2B3A).
Additional Information
IntroductionHuman T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
SynonymsNULL
SourceNULL
Physical AppearanceSterile Filtered clear solution.
Formulation(1mg/ml) 25mM Tris, 250mM Glycine and 0.1% SDS.
StabilityProtein is shipped at ambient temperature. Upon arrival, Store at -20°C.
PurityProtein is >95% pure as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
ApplicationsUse as an antigen in ELISA and Western Blots.
Purification MethodHTLV-I+II was purified by proprietary chromatographic technique.
Background

N/A

Protocol

N/A

MSDS
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