IL 28B Mouse-Interleukin

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IL 28B Mouse

Qty


Total
$65
Catalog #
CYPS-739
Size
Description
IL-28B Mouse Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 174 amino acids and having a molecular mass of 19.6kDa.The IL28B is purified by proprietary chromatographic techniques.
Additional Information
IntroductionIL-28B is a cytokine remotely related to type I interferons and the IL-10 family. Interleukin-28B, interleukin 28A (IL28A), and interleukin 29 (IL29) are 3 closely related cytokine genes which form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by these 3 genes can be induced by viral infection. All 3 cytokines interact with a heterodimeric class II cytokine receptor which consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA).
SynonymsInterferon lambda-3, IFN-lambda-3, Interleukin-28B, IL-28B, Ifnl3, Il28, Il28b, IFL-1, INF-alpha, INF-lambda.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationIL28B protein was lyophilized from a 0.2
SolubilityIt is recommended to reconstitute the lyophilized IL-28B in sterile 18M-cm H2O not less than 100
StabilityLyophilized IL-28B althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL28B should be stored at 4°C between 2-7 days and for future use below -18°C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
Amino Acid SequenceDPVPRATRLP
VEAKDCHIAQ
FKSLSPKELQ
AFKKAKGAIE
KRLLEKDMRC
SSHLISRAWD
LKQLQVQERP
KALQAEVALT
LKVWENINDS
ALTTILGQPL
HTLSHIHSQL
QTCTQLQATA
EPKPPSRRLS
RWLHRLQEAQ
SKETPGCLED
SVTSNLFQLL
LRDLKCVASG
DQCV.
PurityGreater than 97.0% as determined by: (a) Analysis by RP-HPLC.(b) Analysis by SDS-PAGE.
Biological ActivityThe ED50 as determined by an anti-viral assay using human HepG2 cells infected with encephalomyocarditis is less than 30 ng/ml, corresponding to a specific activity of > 3.3
UsageNeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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