IL36B Mouse-Interleukin

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IL36B Mouse

Qty


Total
$65
Catalog #
CYPS-172
Size
Description
IL36B Mouse Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 183 amino acids and having a molecular mass of 21.0kDa.The IL36B is purified by proprietary chromatographic techniques.
Additional Information
IntroductionMouse IL-36b belongs to the IL-1 family that includes IL-1b, IL-1a, IL-1ra, IL-18, IL-36ra (IL1F5), IL-36b (IL1F8), IL-36g (IL1F9), IL-37 (IL1F7) and IL-38 (IL-1F10). The IL-1 family members display a 12 b-strand, b-trefoil configuration, and are thoµght to have ascended from a mutual ancestral gene. Mouse IL-36b/IL-1F8 is a 183 amino acid protein which holds no signal sequence, no prosegment and no potential N-linked glycosylation site(s). Mouse IL-36b like its human homologue is actively secreted. Mouse IL-36?/IL-1F8 shares 61-74% aa homology with human IL-36?/IL-1F8 isoform 2 and rat IL-1F8.
SynonymsInterleukin 36 beta, interleukin 1 family member 8 (eta), Interleukin-1 homolog 2, IL1F8 (Canonical product IL-1F8a), IL-1F8 (FIL1-eta), Interleukin-1 Superfamily e, IL1H2, MGC126880, MGC126882.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered White lyophilized (freeze-dried) powder.
FormulationLyophilized from a 0.2
SolubilityIt is recommended to reconstitute the lyophilized IL36B in sterile 18M-cm H2O not less than 100
StabilityLyophilized IL36B Mouse althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL36B should be stored at 4°C between 2-7 days and for future use below -18°C.Please prevent freeze-thaw cycles.
Amino Acid SequenceMMAFPPQSCV
HVLPPKSIQM
WEPNHNTMHG
SSQSPRNYRV
HDSQQMVWVL
TGNTLTAVPA
SNNVKPVILS
LIACRDTEFQ
DVKKGNLVFL
GIKNRNLCFC
CVEMEGKPTL
QLKEVDIMNL
YKERKAQKAF
LFYHGIEGST
SVFQSVLYPG
WFIATSSIER
QTIILTHQRG
KLVNTNFYIE
SEK
PurityGreater than 95.0% as determined by SDS-PAGE.
Biological ActivityMeasured by its binding ability in a functional ELISA to bind recombinant mouse IL-1 Rrp2.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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