IMPDH1 Human-Dehydrogenase

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IMPDH1 Human

Qty


Total
$65
Catalog #
ENPS-532
Size
Description
IMPDH1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 534 amino acids (1-514 a.a.) and having a molecular mass of 57.5 kDa. The IMPDH1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionIMPDH1 is a rate limiting enzyme in the de novo synthesis of guanine nucleotides and consequently participates in the regulation of cell growth. IMPDH1 takes part in the development of malignancy and the growth progression of some tumors. IMPDH1 performs as a homotetramer to regulate cell growth. IMPDH1 catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5''-monophosphate (IMP). Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10).
SynonymsEC 1.1.1.205, IMP (inosine monophosphate) dehydrogenase 1, LCA11, RP10, IMPDH 1, IMPD 1, IMPDH-I, SwSS2608, DKFZp781N0678.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationIMPDH1 Human solution containing 20mM Tris HCL pH-8, 1mM DTT & 20% glycerol.
StabilityIMPDH1 Human althoµgh stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MADYLISGGT
GYVPEDGLTA
QQLFASADGL
TYNDFLILPG
FIDFIADEVD
LTSALTRKIT
LKTPLISSPMDTVTEADMAI
AMALMGGIGF
IHHNCTPEFQ
ANEVRKVKKF
EQGFITDPVV
LSPSHTVGDV
LEAKMRHGFS
GIPITETGTM
GSKLVGIVTS
RDIDFLAEKD
HTTLLSEVMT
PRIELVVAPA
GVTLKEANEI
LQRSKKGKLP
IVN
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished forLABORATORY RESEARCHUSEONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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