METAP1 Human-Peptidase

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METAP1 Human

Qty


Total
$65
Catalog #
ENPS-611
Size
Description
METAP1 Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 409 amino acids (1-386) and having a molecular mass of 45.7kDa.METAP1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionMethionine aminopeptidase 1 (METAP1) is a member of the peptidase M24A family. METAP1 removes the amino-terminal methionine from nascent proteins. METAP1 releases N-terminal amino acids, preferentially methionine, from peptides and arylamides. METAP1 is essential for normal progression throµgh the cell cycle. The active site of METAP1 contains 2 adjacent divalent metal ions linked by a water molecule or hydroxide ion.
SynonymsMethionine aminopeptidase 1, MAP 1, MetAP 1, Peptidase M 1, METAP1, KIAA0094, MAP1A, MetAP1A.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
FormulationThe METAP1 solution (1mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 3mM DTT, 40% glycerol, 200mM NaCl and 0.1mM PMSF.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MGSMAAVETR
VCETDGCSSE
AKLQCPTCIK
LGIQGSYFCS
QECFKGSWAT
HKLLHKKAKD
EKAKREVSSW
TVEGDINTDP
WAGYRYTGKL
RPHYPLMPTR
PVPSYIQRPD
YADHPLGMSE
SEQALKGTSQ
IKLLSSEDIE
GMRLVCRLAR
EVLDVAAGMIKPGVTTEEID
HAVHLACIAR
NCYPSPLNYY
NFPKSCCTSV
NEVICHGIPD
RRP
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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