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| Introduction | GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thoµght to encode a secreted protein which negatively regulates skeletal muscle growth. |
| Synonyms | GDF-8, MSTN, Growth Differentiation Factor 8, MSTN Muscle Hypertrophy. |
| Source | Nicotiana benthamiana plant |
| Physical Appearance | Sterile Filtered White lyophilized (freeze-dried) powder. |
| Formulation | Lyophilized from 1mg/ml solution in glycine 0.05M buffer at pH 8.5 and 100mM NaCl. |
| Solubility | It is recommended to reconstitute the lyophilized Myostatin in sterile 18M?-cm H2O not less than 100 |
| Stability | Lyophilized Myostatin althoµgh stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Myostatin should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
| Amino Acid Sequence | HHHHHHDFGL DCDEHSTESR CCRYPLTVDF EAFGWDWIIA PKRYKANYCS GECEFVFLQKYPHTHLVHQA NPRGSAGPCC TPTKMSPINM LYFNGKEQII YGKIPAMVVD RCGCS |
| Purity | Greater than 97.0% as determined by Analysis by SDS-PAGE. |
| Usage | NeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
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