NANOG Human, His-NANOG

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NANOG Human, His

Qty


Total
$65
Catalog #
PRPS-888
Size
Description
NANOG Human Recombinant produced in E.coli is a single, non-glycosylated polypeptide chain containing 174 amino acids (1-154) and having a molecular mass of 19.6 kDa.The NANOG is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionNANOG is a multidomain homeobox transcription factor which functions to maintain the undifferentiated state of pluripotent stem cells. NANOG expression counteracts the differentiation-promoting signals induced by the extrinsic factors LIF, Stat3 and BMP. Once NANOG expression is downregulated, cell differentiation can proceed. Proteins which regulate NANOG expression include transcription factors Oct4, SOX2, FoxD3, and Tcf3 and tumor suppressor p53.
SynonymsNANOG, Homeobox protein NANOG, Homeobox transcription factor Nanog, hNanog.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered colorless solution.
FormulationNANOG protein (0.25mg/ml) is supplied in 20mM Tris-HCL, pH-8, 1mM DTT and 20% Glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MSVDPACPQS
LPCFEASDCK
ESSPMPVICG
PEENYPSLQM
SSAEMPHTET
VSPLPSSMDL
LIQDSPDSST
SPKGKQPTSA
EKSVAKKEDK
VPVKKQKTRT
VFSSTQLCVL
NDRFQRQKYL
SLQQMQELSN
ILNLSYKQVK
TWFQNQRMKS
KRWQ
PurityGreater than 90.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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