NFNB E.Coli-Reductase

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NFNB E.Coli

Qty


Total
$65
Catalog #
ENPS-430
Size
Description
NFNB Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 237 amino acids (1-217 a.a.) and having a molecular mass of26 kDa. The NFNB is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.
Additional Information
IntroductionNFNB demonstrates the capability to reduce quinines. NFNB enzyme activates prodrµgs in antibody directed enzyme prodrµg therapy. NFNB reduces nitrofurazone, quinones and anti-tumor agent CB1954 (5-(aziridin-1-yl)-2,4-dinitrobenzamide). The reduction of CB1954 results in the generation of cytotoxic species.
SynonymsDPRA, NFSB, NFSI, NTR.
SourceEscherichia Coli.
Physical AppearanceSterile filtered colorless solution.
Formulation1mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.05M NaCl & 10% glycerol.
StabilityNFNB Human althoµgh stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MDIISVALKR
HSTKAFDASK
KLTPEQAEQI
KTLLQYSPSS
TNSQPWHFIV
ASTEEGKARV
AKSAAGNYVF
NERKMLDASH
VVVFCAKTAM
DDVWLKLVVD
QEDADGRFAT
PEAKAANDKG
RKFFADMHRK
DLHDDAEWMA
KQVYLNVGNF
LLGVAALGLD
AVPIEGFDAA
ILDAEFGLKE
KGYTSLVVVP
VGHHSVEDFN
ATLPKSRLPQ
NI
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific''s products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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