NUDT2 Human-Nudix Type Motif

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NUDT2 Human

Qty


Total
$65
Catalog #
ENPS-070
Size
Description
NUDT2 produced in E.Coli is a single, non-glycosylated polypeptide chain containing 167 amino acids (1-147a.a.) and having a molecular mass of 19.0kDa.NUDT2 is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Additional Information
IntroductionNUDT2 belongs to the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. NUDT2 conserves homeostasis by using water to cleave the metabolite NUDT symmetrically back into its original ATP and AMP molecules. In addition, NUDT2 is active towards other adenosine and diadenosine polyphosphates with four or more phosphate groups, however, not towards diadenosine triphosphate. NUDT2 has a role in heat shock and metabolic stress by regulating intracellular dinucleoside polyphosphate concentrations.
Synonymsnudix (nucleoside diphosphate linked moiety X)-type motif 2, APAH1, Diadenosine 5',5'''-P1,P4-tetraphosphate asymmetrical hydrolase, Diadenosine tetraphosphatase, Nucleoside diphosphate-linked moiety X motif 2, Ap4Aase, EC 3.6.1.17, MGC10404, Ap4A hydrola
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear solution.
FormulationThe NUDT2 protein solution (1mg/1ml) is formulated in 20mM Tris-HCl buffer (pH8.0) 1mM DTT, 0.1M NaCl and 10% glycerol.
Amino Acid SequenceMGSSHHHHHH
SSGLVPRGSH
MALRACGLII
FRRCLIPKVD
NNAIEFLLLQ
ASDGIHHWTP
PKGHVEPGED
DLETALRETQ
EEAGIEAGQL
TIIEGFKREL
NYVARNKPKT
VIYWLAEVKD
YDVEIRLSHE
HQAYRWLGLE
EACQLAQFKE
MKAALQEGHQ
FLCSIEA
PurityGreater than 90% as determined by SDS-PAGE.
UsageNeoScientifics products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
StorageStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time.Please avoid freeze thaw cycles.
Background

N/A

Protocol

N/A

MSDS
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