OPG Human, Hi-5-Osteoprotegerin

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OPG Human, Hi-5

Qty


Total
$65
Catalog #
CYPS-640
Size
Description
Recombinant Osteoprotegerin produced in baculovirus is a signle, glycosylated polypeptide chain containing 398 amino acid residues (22-401 a.a.), having a calculated molecular mass of 45.6 kDa. The Osteoprotegerin is fused to 17 amino acid His tag at C-terminus amd purified by proprietary chromatographic techniques.
Additional Information
IntroductionOsteoprotegerin acts as decoy receptor for rankl and thereby neutralizes its function in osteoclastogenesis. OPG inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local rankl/opg ratio. Osteoprotegerin may also play a role in preventing arterial calcification. May act as decoy receptor for trail and protect against apoptosis. Trail binding blocks the inhibition of osteoclastogenesis.
SynonymsTNFRSF11B, OPG, OCIF, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TR1, MGC29565.
SourceHi-5.
Physical AppearanceSterile Filtered colorless clear solution.
FormulationOsteoprotegerin protein contains PBS pH-7.4 and 10% glycerol.
StabilityStore at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.
Amino Acid SequenceADPETFPPKY
LHYDEETSHQ
LLCDKCPPGT
YLKQHCTAKW
KTVCAPCPDH
YYTDSWHTSD
ECLYCSPVCK
ELQYVKQECN
RTHNRVCECK
EGRYLEIEFC
LKHRSCPPGF
GVVQAGTPER
NTVCKRCPDG
FFSNETSSKA
PCRKHTNCSV
FGLLLTQKGN
ATHDNICSGN
SESTQKCGID
VTLCEEAFFR
FAVPTKFTPNWLSVLVDNLP
GTKVNAESVE
RIKRQHSSQE
QTF
PurityGreater than 85.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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