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+1-888.733.6849
+1-617.299.7367 (Int’l)
Introduction | PRTN3 is a polymorphonuclear leukocyte serine protease which degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro) and causes emphysema once managed by tracheal insufflation to hamsters. |
Synonyms | AGP7, P29, PR-3, ACPA, C-ANCA, MBT, MBN, Leukocyte proteinase 3, Neutrophil proteinase 4, Wegener granulomatosis autoantigen, Azurophil granule protein 7, myeloblastin, Serine proteinase neutrophil. |
Source | Native. |
Formulation | PRTN3 is supplied in 16mM HEPES buffer pH-8.0, 400mM NaCl, and 20% glycerol. |
Purity | Greater than 80% in the sum of different glycosylation isoforms according to following section as determined by SDS-PAGE and capillary electrophoresis. |
Usage | NeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals. |
Applications | Western blot with rabbit anti-PR3 antisera and mouse anti-PR3 monoclonal antibodies. |
Storage | Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles. |
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