PSMB1 Human-Proteasome

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PSMB1 Human

Qty


Total
$65
Catalog #
ENPS-412
Size
Description
PSMB1 Human Recombinant fused to 37 amino acid His Tag at N-terminal produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 250 amino acids (30-241) and having a molecular mass of 27.7 kDa. The PSMB1 is purified by proprietary chromatographic techniques.
Additional Information
IntroductionPSMB1 is part of the proteasome B-type family, also identified as the T1B family, that is a 20S core beta subunit. PSMB1 is tightly linked to the TBP (TATA-binding protein) gene in human and in mouse, and is transcribed in the opposite orientation in both species.The main function of PSMB1 is its degradation activity of unnecessary or damaged proteins by proteolysis. PSMB1 is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with arg, phe, tyr, leu, and glu adjacent to the leaving group at neutral or slightly basic ph. the proteasome has an atp-dependent proteolytic activity.
SynonymsHC5, PSC5, PMSB1, FLJ25321, KIAA1838, PSMB1, Proteasome subunit beta type-1, Proteasome component C5, Macropain subunit C5, Multicatalytic endopeptidase complex subunit C5, Proteasome gamma chain.
SourceEscherichia Coli.
Physical AppearanceSterile Filtered clear colorless solution.
FormulationThe PSMB1 solution contains 20mM Tris-HCl pH-8, 1mM DTT and 10% glycerol.
StabilityPSMB1 Recombinant Human althoµgh stable at 4°C for 30 days, should be stored desiccated below -20°C for periods greater than 30 days. Please avoid freeze-thaw cycles.
Amino Acid SequenceMRGSHHHHHH
GMASMTGGQQ
MGRDLYDDDD
KDRWGSHMFS
PYVFNGGTIL
AIAGEDFAIV
ASDTRLSEGF
SIHTRDSPKC
YKLTDKTVIG
CSGFHGDCLT
LTKIIEARLK
MYKHSNNKAM
TTGAIAAMLS
TILYSRRFFP
YYVYNIIGGL
DEEGKGAVYS
FDPVGSYQRD
SFKAGGSASA
MLQPLLDNQV
GFKNMQNVEH
VPLSLDRAMR
LVKDVFISAA
ERDVYTGDAL
RI
PurityGreater than 95.0% as determined by SDS-PAGE.
UsageNeoScientific's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drµgs, agricultural or pesticidal products, food additives or household chemicals.
Background

N/A

Protocol

N/A

MSDS
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